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'b? 7I?a?/bs{[??Ho[Hon?????^??y9???U o(?H:??y??"?EB?R??}R?????&??x"????]? zk?v"???/EW??)??`????o?=??!N?ڢ?ko6r?_?E?^ѐxܝ???b ?)#r?E$0|?-?)p?K!?Ίӭ? ?=? ??\?ͱ?;z???? ߿>RZjʲ9=???T?ԭ???tl?m&?G?????? 55 endstreamendobj5 0 obj<>/Font<>/ProcSet[/PDF/Text]/Properties<>/ExtGState<>>>/Type/Page/LastModified(D:20250115165239+05'30')>>endobj6 0 obj<>stream H??W?r???m?{??CB?'?f2CI???]??^H??X???D3??WLz?]??L?^5??L??w?s??gt???ck5????c???????j޴r??????{v???e??x}{?F??>??^??? ?????j4??8cA?Q??s??O?b;r?0/>?^??!???Ҹ???q??/?S˜_??w??;??37???I\vU??Y#?웓7???Q??, ?Ͽw???8?w?gN?%?rѺy??k??D?v???ù??-??a???_?N???z?Q????8?9u?"/Ʃox?????t?:??,ˡ?oy?f?????ϛA?L1mɘ$?yK??M???}^?lǑx.ql??????}?T??n?n??^4?֯$?!???Sϝ?36?? 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I/??C?ޠ}?f6?zנNt, וFA???~y[??t???v?/k?$??Ź)??p?uH??͵??B"W??z???1z?wi=:?;?4?-%?????p?Q)c??$??Ȁ?c3xƠe`???˲CE?v1?'??j????7)t7???gEn?>???=C?KY????b?S.DA????k??F? oHg??/?S˜_???\?h?}??Г|3#???P}h????x~??^???0?{G?aGG????a??5??[u?A?0??ղ?q}???"8C??}?*l?¡?;7?0$ 1ȝ???/???@?5ۜ?e$?U]U???0?Wj)~?Ư????.C?fm=[?\??{???Xcϱ??M3w????!?A&?~)??"?9??zAƷ??[?U?׫mX̑?`Ĺ?*?u N??J???+?]????zK??l??i??"?t?B*?ɗ?;,??=i'?AO?;U???6zb?0??j??(?At?)?p?L?UP????2L? ??*?!??i?q?[?~ݾ?c?XYm?U??????# 9]3??,,C^??/Q?O??n?v??(??V??XwXo?f_??_?c??Pm O?9{???U ??+???G?w?W,????4z1g??Rc@]J?R??Q?@?????????D^?U?(???o?M??"w??R?? oĈv>U?Wi??Û?i????J?8E??Dժ?.?8?Q,?? ??V?JK??y8?x??,z?|?%nlձE ???mQ?.tCX ? ?"M?tX$p5?:??q>8?? 39D??_s6??j& @5W??0r?e??֠???Ƶ?@??s????p????x???E?X???{D?K?*ð?DX= ???VE??$?8i%zF???Q?n?񇣻p??F?mb?3d`? ??~?? .?It:?B\E?Q??9.$??,?? <+??$??K?%?G3:???J4xްm??K?֑?k??ӑ???3D?w?ѰD_k??"??hE????$r??T?ջ?,??f?‚8?U)???\??????d8IQ???X?h??M?+?SEz?3Q???O? ????:3???uv??!al1?G?dr$????T??3?? g]????J?~???̐??????F<#????j???????4kY8H??G1?gʇ>?b?BP?lঅZ?Q????rSø???-?,?X"Tgz#79޲??{??C?/l??i?]??i,??z???N Kqӱ?v>?Q???????7?}x<Un?s,?2?)*'Mb-$????v??j5?9x*B??0?????????c??????\??"Q??????[g~??5??R???s?rO?V?q?Db?N??/?\(B????8&?@?`Ø ؘ?BL?씜? ,k?? ??Z?͠???????s??Q~??`/?X޼?mq2??]YM%?Y??(+??7??F?????x????ߎID|?h?#m*?m????-??7a?' ?M??3Dـ??1sL???f8R$???iQ????ҽ?r?p[}\?Bc???5sOB >stream application/postscript master_template_NEW carvethk Adobe Illustrator 28.3 (Macintosh) 2024-12-02T15:10:42Z 2024-12-02T15:10:42Z 2024-12-02T15:10:42Z xmp.did:a2bdd1c2-016d-42f1-8ecd-0ef938689389 xmp.iid:a2fc68c5-944e-4fe6-aa4d-6fc27c4ad60b uuid:AD83186F157FE111B718E1DB816FAC55 xmp.iid:d0342ccd-f2e1-430e-9b06-9b9e34c0ed98 xmp.did:422b06e1-33f2-4970-8b08-74dea9813fc9 uuid:AD83186F157FE111B718E1DB816FAC55 converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F87F1174072068118C1490BD3450264E 2012-04-23T11:19:36+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:05801174072068118A6DA55D7C3CC575 2012-07-11T14:51:09+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:07801174072068118A6DACF15F0EB62C 2012-07-26T16:37:46+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F87F1174072068118C149559DC443FEC 2012-08-01T11:25:17+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F87F1174072068118C14A38F6229F1F1 2012-08-23T11:14:21+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F87F1174072068118C1493EF43C88303 2012-10-11T10:33:05+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:02801174072068118A6DC1596EF99E65 2012-10-23T16:25:45+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:00801174072068118C1484815E63F097 2012-11-02T16:47:59Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:FA7F1174072068118C14A120EFE05BF1 2012-11-16T12:41:53Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F87F1174072068118A6DF04774FFAF95 2013-02-05T09:58Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F97F1174072068118C14CAC8257C613F 2013-02-13T15:51:25Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:02801174072068118A6DDF5F52C3CE40 2013-03-01T10:33:26Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F97F1174072068118A6DBFDE4657CB8A 2013-03-26T14:35:22Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F87F1174072068118083DB36AF47DF40 2013-09-02T09:51:34+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:FA7F1174072068118083FD8407E13F19 2013-09-20T14:32:50+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:02801174072068118083B7C8845F4D18 2013-11-01T09:03:57Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F87F117407206811822ACCE1ADC987F1 2013-11-12T09:18:44Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F97F117407206811822ACCE1ADC987F1 2013-11-12T14:34:42Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:06801174072068118083A926A9FDDC64 2013-11-27T16:11:02Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F87F1174072068118083D282D608275D 2014-04-01T09:50:23+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:05801174072068118083D948F07CDF56 2014-04-24T15:45:28+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:FD7F11740720681180839D7921C7CB48 2014-06-30T16:47:30+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:FD7F117407206811808395CC92700BBD 2014-07-03T14:48:09+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:FA7F117407206811808399405CCA1345 2014-08-20T14:27:37+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:FD7F117407206811808399405CCA1345 2014-08-20T15:12:10+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:01801174072068118083AA8BDDA8B484 2014-09-01T10:26:44+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:0280117407206811808382C20B036DF1 2014-09-08T11:33:57+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:03801174072068118083F3C65F88F76C 2014-10-01T12:30:55+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:02801174072068118083EBC0F1E698A4 2014-10-23T12:31:37+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:028011740720681180839C7FAF1E9798 2015-03-02T09:40:49Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:02801174072068118083C23BE8437FF5 2015-03-16T09:56:12Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:02801174072068118083E611FF3FA1B5 2015-04-01T10:19:43+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:F77F117407206811822AA7A5EF73441D 2015-04-28T16:19:49+01:00 Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:02801174072068118083D86CCAC48E5A 2015-11-02T10:43:30Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:01801174072068118083D8049619A9DD 2015-11-03T09:28:50Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:FC7F1174072068118083CBB48ADED86F 2016-02-02T12:27:41Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:FD7F1174072068118083CBB48ADED86F 2016-02-02T16:03:04Z Adobe Illustrator CS5 / converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator converted from application/postscript to application/vnd.adobe.illustrator saved xmp.iid:FD7F117407206811808384D3411D69FB 2016-04-01T14:50:15+01:00 Adobe Illustrator 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>endobj122 0 obj<>endobj123 0 obj<>endobj124 0 obj<>endobj125 0 obj<>stream application/pdf doi:10.1016/S0140-6736(24)02420-6 Appendicectomy versus antibiotics for acute uncomplicated appendicitis in children: an open-label, international, multicentre, randomised, non-inferiority trial Prof Shawn D St Peter MD Janelle R Noel-MacDonnell PhD Prof Nigel J Hall MD PhD Prof Simon Eaton PhD Janne S Suominen MD Prof Tomas Wester MD PhD Prof Jan F Svensson MD PhD Markus Almström MD PhD E Pete Muenks MSc Prof Marianne Beaudin MD Prof Nelson Piché MD Prof Mary Brindle MD MPH Ali MacRobie Prof Richard Keijzer MD PhD Prof Helene Engstrand Lilja MD PhD Ann-Marie Kassa RN PhD Prof Tim Jancelewicz MD Prof Andreana Butter MD Jacob Davidson MSc Prof Erik Skarsgard MD Yap Te-Lu MD Shireen Nah MD Prof Andrew R Willan PhD Prof Agostino Pierro MD PhD The Lancet, 405 (2025) 233-240. doi:10.1016/S0140-6736(24)02420-6 Elsevier Ltd journal The Lancet Copyright © 2025 Elsevier Ltd. All rights reserved. 0140-6736 405 10474 18 January 2025 2025-01-18 233-240 233 240 10.1016/S0140-6736(24)02420-6 http://dx.doi.org/10.1016/S0140-6736(24)02420-6 2010-04-23 true 10.1016/S0140-6736(24)02420-6 elsevier.com sciencedirect.com VoR <6mIUqn9qMnwn.zgiGndyRncNNmt7-lweMmt2GowmSmwz_nPn9m9qQo9eQndmMm9aKnteTma/> 10.1016/S0140-6736(24)02420-6 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2025-01-15T05:18:52+05:30 2025-02-06T13:03:18+05:30 2025-02-06T13:03:18+05:30 True Adobe PDF Library 15.0 False uuid:cf524159-0ea8-47a7-8f8b-51a370aab0fc uuid:bb18ba9b-7cd5-40d2-aab7-f92325744de0 endstreamendobj126 0 obj<>endobjxref 0 127 0000000000 65535 f 0000054604 00000 n 0000055020 00000 n 0000060089 00000 n 0000060518 00000 n 0000064772 00000 n 0000065250 00000 n 0000070176 00000 n 0000180561 00000 n 0000180596 00000 n 0000181050 00000 n 0000186458 00000 n 0000186900 00000 n 0000191912 00000 n 0000192331 00000 n 0000197023 00000 n 0000197453 00000 n 0000203571 00000 n 0000203914 00000 n 0000204361 00000 n 0000204660 00000 n 0000208260 00000 n 0000208695 00000 n 0000209051 00000 n 0000209513 00000 n 0000209924 00000 n 0000210036 00000 n 0000210085 00000 n 0000210130 00000 n 0000210173 00000 n 0000211365 00000 n 0000211455 00000 n 0000211532 00000 n 0000211651 00000 n 0000211713 00000 n 0000211734 00000 n 0000212203 00000 n 0000212417 00000 n 0000212492 00000 n 0000212550 00000 n 0000212624 00000 n 0000212685 00000 n 0000212759 00000 n 0000212818 00000 n 0000212863 00000 n 0000212922 00000 n 0000212965 00000 n 0000213024 00000 n 0000213093 00000 n 0000213162 00000 n 0000213232 00000 n 0000213289 00000 n 0000213375 00000 n 0000213442 00000 n 0000213507 00000 n 0000213571 00000 n 0000213618 00000 n 0000213665 00000 n 0000213712 00000 n 0000213770 00000 n 0000213826 00000 n 0000213894 00000 n 0000213941 00000 n 0000213985 00000 n 0000214020 00000 n 0000214078 00000 n 0000214134 00000 n 0000214202 00000 n 0000214249 00000 n 0000214293 00000 n 0000214328 00000 n 0000214386 00000 n 0000214442 00000 n 0000214509 00000 n 0000214711 00000 n 0000214765 00000 n 0000214819 00000 n 0000214864 00000 n 0000214909 00000 n 0000214954 00000 n 0000214999 00000 n 0000215044 00000 n 0000215089 00000 n 0000215134 00000 n 0000215179 00000 n 0000215224 00000 n 0000215269 00000 n 0000215314 00000 n 0000215359 00000 n 0000215404 00000 n 0000215449 00000 n 0000215494 00000 n 0000215539 00000 n 0000215584 00000 n 0000215629 00000 n 0000215673 00000 n 0000215717 00000 n 0000215761 00000 n 0000215796 00000 n 0000215831 00000 n 0000215866 00000 n 0000215902 00000 n 0000215938 00000 n 0000215974 00000 n 0000216010 00000 n 0000216046 00000 n 0000216082 00000 n 0000216118 00000 n 0000216154 00000 n 0000216190 00000 n 0000216226 00000 n 0000216262 00000 n 0000216298 00000 n 0000216334 00000 n 0000216370 00000 n 0000216406 00000 n 0000216442 00000 n 0000216478 00000 n 0000216514 00000 n 0000216550 00000 n 0000216586 00000 n 0000216622 00000 n 0000216658 00000 n 0000216696 00000 n 0000216729 00000 n 0000216829 00000 n 0000225076 00000 n trailer <> startxref 116 %%EOF